Implementing non-invasive markers for liver fibrosis in clinical practice

Clinical Application of Non-Invasive Markers of Liver Fibrosis

Liver is one of the most important organs in our body and any damage on this vital organ may be life threatening. Various factors such as toxins, heavy metals, drugs and infection with hepatitis viruses are able to influence on the function of this organ. One of the most important effects of these factors on liver is gradual necrosis of active liver cells and if this disturbance remained untrea...

Non-invasive Assessment of Liver Fibrosis Using Serum Markers

Fibrosis is an intrinsic response to chronic injury, that elicits excess deposition of matrix compounds and scarring, which ultimately alters liver structure and function. Liver biopsy has long been the gold standard for assessing the degree of liver fibrosis. Due to liver biopsy invasiveness, specialists and patients favor alternative non-invasive tests for fibrosis staging. In recent years, m...

Non-Invasive markers for hepatic fibrosis

With great advancements in the therapeutic modalities used for the treatment of chronic liver diseases, the accurate assessment of liver fibrosis is a vital need for successful individualized management of disease activity in patients. The lack of accurate, reproducible and easily applied methods for fibrosis assessment has been the major limitation in both the clinical management and for resea...

Non-invasive markers associated with liver fibrosis in non-alcoholic fatty liver disease.

The diagnosis of fibrosis within liver disease is important for prognosis, stratification for treatment, and monitoring of treatment efficacy. The rising incidence and prevalence of non-alcoholic fatty liver disease (NAFLD) has driven the search for accurate non-invasive tools of liver fibrosis within this condition. With the aid of a systematic review, we explore how the field has evolved from...

usefulness of non-invasive tools in liver fibrosis assessment